Endocrine Abstracts

Introduction: Adult growth hormone deficiency is associated with fatigue, tiredness and myalgias. The same clinical pattern can often be present in oncological patients during chemotherapy and follow up.Aim of the study: To conduct an extensive neuromuscular investigation of patients with breast cancer (BC), treated with taxol, in an attempt to explain their neuromuscular symptoms, eleven pre-menopausal patients with BC underwent a prospective protocol, ...

The highly toxic heavy metal Cadmium (Cd) is widely spread in the environment and could exert estrogen-like activity in tissues including breast. Previous studies demonstrated that Cd binds to estrogen receptor α positive (ERα+) breast cancer (BC) cells. In this new study, we evaluated effects of Cd on both ERα+ and ERα negative (ERα-) BC models with the aim to further characterize the mechanisms involved in Cd-related BC carcinogenesis. Specifically, ...